ANGOR DE PRINZMETAL PDF

It can also occur at rest, and even at night which should suggest a variant angina by coronary spasm. They may also mask the signs of hyperthyroidism and cause worsening of Prinzmetal angina , severe peripheral and central circulatory disorders and hypotension. An unstable angina particular case is variant angina , or angina friendly, electively occurring late at night and especially accompanied by arrhythmias. Beta-blockers may also mask the signs of hyperthyroidism and cause worsening of Prinzmetal angina , severe peripheral and central circulatory disorders and hypotension. Next came highly regarded studies on the Prinzmetal variant of angina , the effects of certain medications such as calcium antagonists and thrombolytic agents, among others.

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It can also occur at rest, and even at night which should suggest a variant angina by coronary spasm. They may also mask the signs of hyperthyroidism and cause worsening of Prinzmetal angina , severe peripheral and central circulatory disorders and hypotension. An unstable angina particular case is variant angina , or angina friendly, electively occurring late at night and especially accompanied by arrhythmias.

Beta-blockers may also mask the signs of hyperthyroidism and cause worsening of Prinzmetal angina , severe peripheral and central circulatory disorders and hypotension. Next came highly regarded studies on the Prinzmetal variant of angina , the effects of certain medications such as calcium antagonists and thrombolytic agents, among others.

Angina as a result of a coronary artery spasm is called "variant" angina or Prinzmetal angina. Prinzmetal angina typically occurs at rest, usually in the early morning hours.

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Angor d’effort

Dit komt door een krampachtige samentrekking van het bloedvat vaatspasmen. Deze spasmen veroorzaken zuurstofgebrek in de achterliggende hartspier. Deze vorm van angina pectoris komt niet vaak voor. De arts ziet geen opvallende vernauwingen er zijn geen stolsels aanwezig Prinzmetal angina pectoris wordt ook coronair vaatspasme of variant angina genoemd. Oorzaken De oorzaak van Prinzmetal angina pectoris is onduidelijk. Om dit te ontdekken is meer onderzoek nodig.

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Le Angor de Prinzmetal est-il héréditaire ?

Mechanism[ edit ] The mechanism that causes such intense vasospasm, as to cause a clinically significant narrowing of the coronary arteries is so far unknown, but there are three relevant hypotheses: Enhanced contractility of coronary vascular smooth muscle due to reduced nitric oxide bioavailability caused by a defect in the endothelial nitric oxide synthetase enzyme which leads to endothelial function abnormalities. NO then diffuses out of the endothelial cells, stimulating relaxation of the nearby smooth muscle cells. In healthy arterial walls, the overall indirect relaxation induced by acetylcholine via nitric oxide is of greater effect than any contraction that is induced. When the endothelium is dysfunctional, stimulation with acetylcholine will fail to produce, or produce very little, nitric oxide. Thus, acetylcholine released by the PSNS at rest will simply cause contraction of the vascular smooth muscle. Abnormal platelet activation e. Individuals who develop cardiac chest pain are generally treated empirically as an " acute coronary syndrome ", and are immediately tested for elevations in their blood levels of enzymes such as creatine kinase isoenzymes or troponin that are markers for cardiac damage.

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